Convinced that his buddy Nardo is making the mistake of a lifetime by marrying Tracy, Jason puts a dramatic end to their wedding. When the furious bride decides to take her Baja honeymoon solo, Nardo follows her, and the lovesick groom gets carjacked and is left stranded, naked and penniless in a remote part of the Mexican desert. Helpless, Nardo sends out an SOS to Jason and their pal Evan, an up-and-coming ad exec who is slated for an important business meeting the next morning. During their ridiculous attempt to rescue Nardo, the trio embarks on a series of increasingly outrageous misadventures involving con artists, drug smugglers and even the Federales.
T.J. Miller, Adam Pally, Thomas Middleditch, Alison Brie, Shannon Marie Woodward, Krysten Ritter, Lance Reddick, Rosa Salazar, Jason Mantzoukas, J.B. Smoove, Brian Huskey, Jon Glaser, Octavio Gomez, Maurice Compte, Laurie Singer, Codi Fischer, Tracy Vilar, Seth Nichols, Billy Merritt, Richard Holden, Timmy Mayse, Eric Filipkowski, Jesse Falcon, Robert Armstrong, Horatio Sanz, Joseph A Nunez, Daniel Zacapa, Riki Lindhome, Kate Micucci, Peaches Davis, Brad Morris